Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1967834..1967979 Replicon chromosome
Accession NZ_LR890686
Organism Klebsiella pneumoniae isolate INF201-sc-2280069

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1967870..1967972 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1967834..1967979 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX24_RS09445 1962964..1965024 + 2061 WP_032419805.1 oligopeptidase B -
JMX24_RS09450 1965028..1965687 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMX24_RS09455 1965766..1965996 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX24_RS09460 1966109..1966483 + 375 WP_020316569.1 CopC domain-containing protein YobA -
JMX24_RS09465 1966487..1967356 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMX24_RS09470 1967373..1967711 + 339 WP_002911404.1 YebY family protein -
- 1967834..1967979 - 146 - - Antitoxin
- 1967870..1967972 + 103 - - Toxin
JMX24_RS09475 1968347..1968490 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMX24_RS09480 1968595..1969563 - 969 WP_014907334.1 VirK/YbjX family protein -
JMX24_RS09485 1969720..1970373 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
JMX24_RS09490 1970370..1970561 - 192 WP_002911395.1 YebW family protein -
JMX24_RS09495 1970659..1970898 - 240 WP_002911393.1 YebV family protein -
JMX24_RS09500 1971014..1972447 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291820 NZ_LR890686:1967870-1967972 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291820 NZ_LR890686:c1967979-1967834 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References