Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1832559..1832704 Replicon chromosome
Accession NZ_LR890669
Organism Klebsiella pneumoniae isolate INF321-sc-2280120

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1832595..1832697 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1832559..1832704 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW44_RS08935 1827689..1829749 + 2061 WP_004151449.1 oligopeptidase B -
JMW44_RS08940 1829753..1830412 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW44_RS08945 1830491..1830721 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMW44_RS08950 1830834..1831208 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW44_RS08955 1831212..1832081 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMW44_RS08960 1832098..1832436 + 339 WP_016529031.1 YebY family protein -
- 1832559..1832704 - 146 - - Antitoxin
- 1832595..1832697 + 103 - - Toxin
JMW44_RS08965 1833071..1833214 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW44_RS08970 1833319..1834287 - 969 WP_004151446.1 VirK/YbjX family protein -
JMW44_RS08975 1834444..1835097 + 654 WP_064179133.1 protein-serine/threonine phosphatase -
JMW44_RS08980 1835094..1835285 - 192 WP_002911395.1 YebW family protein -
JMW44_RS08985 1835383..1835622 - 240 WP_002911393.1 YebV family protein -
JMW44_RS08990 1835738..1837171 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291783 NZ_LR890669:1832595-1832697 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291783 NZ_LR890669:c1832704-1832559 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References