Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1876830..1876975 Replicon chromosome
Accession NZ_LR890665
Organism Klebsiella pneumoniae isolate INF065-sc-2279980

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1876866..1876968 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1876830..1876975 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX32_RS09015 1871960..1874020 + 2061 WP_004151449.1 oligopeptidase B -
JMX32_RS09020 1874024..1874683 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMX32_RS09025 1874762..1874992 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX32_RS09030 1875105..1875479 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX32_RS09035 1875483..1876352 + 870 WP_048331959.1 copper homeostasis membrane protein CopD -
JMX32_RS09040 1876369..1876707 + 339 WP_016529031.1 YebY family protein -
- 1876830..1876975 - 146 - - Antitoxin
- 1876866..1876968 + 103 - - Toxin
JMX32_RS09045 1877344..1877487 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMX32_RS09050 1877592..1878560 - 969 WP_074185275.1 DUF535 family protein -
JMX32_RS09055 1878717..1879370 + 654 WP_032447686.1 protein-serine/threonine phosphatase -
JMX32_RS09060 1879367..1879558 - 192 WP_002911395.1 YebW family protein -
JMX32_RS09065 1879656..1879895 - 240 WP_002911393.1 YebV family protein -
JMX32_RS09070 1880011..1881444 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291763 NZ_LR890665:1876866-1876968 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291763 NZ_LR890665:c1876975-1876830 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References