Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 181200..181672 Replicon chromosome
Accession NZ_LR890657
Organism Serratia marcescens isolate MSB1_9C-sc-2280320

Toxin (Protein)


Gene name relE Uniprot ID A0A5P6GNV0
Locus tag JMX15_RS00845 Protein ID WP_048232401.1
Coordinates 181397..181672 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JMX15_RS00840 Protein ID WP_033649649.1
Coordinates 181200..181397 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX15_RS00810 176383..177651 + 1269 WP_055313077.1 glycerol-3-phosphate dehydrogenase subunit GlpB -
JMX15_RS00815 177648..178847 + 1200 WP_055313079.1 anaerobic glycerol-3-phosphate dehydrogenase subunit C -
JMX15_RS00820 178883..179446 - 564 WP_047729417.1 DcrB family lipoprotein -
JMX15_RS00825 179527..179961 - 435 WP_048232398.1 GNAT family N-acetyltransferase -
JMX15_RS00830 180013..180672 - 660 WP_047729415.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
JMX15_RS00835 180893..181138 + 246 WP_025304890.1 sulfurtransferase TusA -
JMX15_RS00840 181200..181397 + 198 WP_033649649.1 hypothetical protein Antitoxin
JMX15_RS00845 181397..181672 + 276 WP_048232401.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
JMX15_RS00850 181732..184050 - 2319 WP_048232403.1 zinc/cadmium/mercury/lead-transporting ATPase -
JMX15_RS00855 184733..186196 + 1464 WP_038874135.1 serralysin family metalloprotease -
JMX15_RS00860 186252..186629 + 378 WP_038874139.1 AprI/Inh family metalloprotease inhibitor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10666.57 Da        Isoelectric Point: 11.2806

>T291744 WP_048232401.1 NZ_LR890657:181397-181672 [Serratia marcescens]
MLNIEWTRVARQDLGEIVGFIANDNPLAARKMKALIMEAVIPAARHPRIFRRGRVDGTHEIPLHPHYLLVYQVLETHIRV
LRVLHTRRQYP

Download         Length: 276 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7398.49 Da        Isoelectric Point: 4.4143

>AT291744 WP_033649649.1 NZ_LR890657:181200-181397 [Serratia marcescens]
MSILLLPTVAKMENEERTQGYERWFLERVQEAMDEPRPGIPHDDVMAEMDAVIAAAEARIKAKQA

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5P6GNV0

Antitoxin

Source ID Structure

References