Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1874447..1874592 Replicon chromosome
Accession NZ_LR890648
Organism Klebsiella pneumoniae isolate INF266-sc-2280182

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1874483..1874585 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1874447..1874592 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW87_RS08985 1869577..1871637 + 2061 WP_004151449.1 oligopeptidase B -
JMW87_RS08990 1871641..1872300 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW87_RS08995 1872379..1872609 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMW87_RS09000 1872722..1873096 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW87_RS09005 1873100..1873969 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
JMW87_RS09010 1873986..1874324 + 339 WP_009307539.1 YebY family protein -
- 1874447..1874592 - 146 - - Antitoxin
- 1874483..1874585 + 103 - - Toxin
JMW87_RS09015 1874961..1875104 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW87_RS09020 1875212..1876177 - 966 Protein_1758 DUF535 domain-containing protein -
JMW87_RS09025 1876334..1876987 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
JMW87_RS09030 1876984..1877175 - 192 WP_002911395.1 YebW family protein -
JMW87_RS09035 1877273..1877512 - 240 WP_002911393.1 YebV family protein -
JMW87_RS09040 1877628..1879061 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291693 NZ_LR890648:1874483-1874585 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291693 NZ_LR890648:c1874592-1874447 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References