Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1829441..1829586 Replicon chromosome
Accession NZ_LR890643
Organism Klebsiella pneumoniae isolate INF346-sc-2280166

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1829477..1829579 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1829441..1829586 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW14_RS08850 1824571..1826631 + 2061 WP_004151449.1 oligopeptidase B -
JMW14_RS08855 1826635..1827294 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW14_RS08860 1827373..1827603 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMW14_RS08865 1827716..1828090 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW14_RS08870 1828094..1828963 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMW14_RS08875 1828980..1829318 + 339 WP_004189269.1 YebY family protein -
- 1829441..1829586 - 146 - - Antitoxin
- 1829477..1829579 + 103 - - Toxin
JMW14_RS08880 1829953..1830096 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW14_RS08885 1830201..1831169 - 969 WP_004151446.1 VirK/YbjX family protein -
JMW14_RS08890 1831326..1831979 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
JMW14_RS08895 1831976..1832167 - 192 WP_002911395.1 YebW family protein -
JMW14_RS08900 1832265..1832504 - 240 WP_002911393.1 YebV family protein -
JMW14_RS08905 1832620..1834053 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291678 NZ_LR890643:1829477-1829579 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291678 NZ_LR890643:c1829586-1829441 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References