Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 550604..550749 | Replicon | chromosome |
| Accession | NZ_LR890640 | ||
| Organism | Klebsiella pneumoniae isolate INF344-sc-2280162 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 550640..550742 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 550604..550749 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMW76_RS02680 | 545734..547794 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| JMW76_RS02685 | 547798..548457 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| JMW76_RS02690 | 548536..548766 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| JMW76_RS02695 | 548879..549253 | + | 375 | WP_201524362.1 | CopC domain-containing protein YobA | - |
| JMW76_RS02700 | 549257..550126 | + | 870 | WP_104158933.1 | copper homeostasis membrane protein CopD | - |
| JMW76_RS02705 | 550143..550481 | + | 339 | WP_016529031.1 | YebY family protein | - |
| - | 550604..550749 | - | 146 | - | - | Antitoxin |
| - | 550640..550742 | + | 103 | - | - | Toxin |
| JMW76_RS02710 | 551119..551259 | - | 141 | Protein_525 | Ecr family regulatory small membrane protein | - |
| JMW76_RS02715 | 551364..552332 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| JMW76_RS02720 | 552489..553142 | + | 654 | WP_020802220.1 | protein-serine/threonine phosphatase | - |
| JMW76_RS02725 | 553139..553330 | - | 192 | WP_002911395.1 | YebW family protein | - |
| JMW76_RS02730 | 553428..553667 | - | 240 | WP_002911393.1 | YebV family protein | - |
| JMW76_RS02735 | 553783..555216 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 496918..555171 | 58253 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T291655 NZ_LR890640:550640-550742 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT291655 NZ_LR890640:c550749-550604 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
