Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1868638..1868783 Replicon chromosome
Accession NZ_LR890624
Organism Klebsiella pneumoniae isolate INF242-sc-2280140

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1868674..1868776 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1868638..1868783 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX20_RS09010 1863768..1865828 + 2061 WP_004151449.1 oligopeptidase B -
JMX20_RS09015 1865832..1866491 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMX20_RS09020 1866570..1866800 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX20_RS09025 1866913..1867287 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX20_RS09030 1867291..1868160 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
JMX20_RS09035 1868177..1868515 + 339 WP_002911404.1 YebY family protein -
- 1868638..1868783 - 146 - - Antitoxin
- 1868674..1868776 + 103 - - Toxin
JMX20_RS09040 1869151..1869294 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMX20_RS09045 1869399..1870367 - 969 WP_181854232.1 VirK/YbjX family protein -
JMX20_RS09050 1870569..1871177 + 609 WP_201530401.1 protein-serine/threonine phosphatase -
JMX20_RS09055 1871174..1871365 - 192 WP_002911395.1 YebW family protein -
JMX20_RS09060 1871463..1871702 - 240 WP_002911393.1 YebV family protein -
JMX20_RS09065 1871818..1873251 - 1434 WP_023157970.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291620 NZ_LR890624:1868674-1868776 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291620 NZ_LR890624:c1868783-1868638 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References