Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1868638..1868783 | Replicon | chromosome |
| Accession | NZ_LR890624 | ||
| Organism | Klebsiella pneumoniae isolate INF242-sc-2280140 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1868674..1868776 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1868638..1868783 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMX20_RS09010 | 1863768..1865828 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| JMX20_RS09015 | 1865832..1866491 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| JMX20_RS09020 | 1866570..1866800 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| JMX20_RS09025 | 1866913..1867287 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| JMX20_RS09030 | 1867291..1868160 | + | 870 | WP_004891049.1 | copper homeostasis membrane protein CopD | - |
| JMX20_RS09035 | 1868177..1868515 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1868638..1868783 | - | 146 | - | - | Antitoxin |
| - | 1868674..1868776 | + | 103 | - | - | Toxin |
| JMX20_RS09040 | 1869151..1869294 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| JMX20_RS09045 | 1869399..1870367 | - | 969 | WP_181854232.1 | VirK/YbjX family protein | - |
| JMX20_RS09050 | 1870569..1871177 | + | 609 | WP_201530401.1 | protein-serine/threonine phosphatase | - |
| JMX20_RS09055 | 1871174..1871365 | - | 192 | WP_002911395.1 | YebW family protein | - |
| JMX20_RS09060 | 1871463..1871702 | - | 240 | WP_002911393.1 | YebV family protein | - |
| JMX20_RS09065 | 1871818..1873251 | - | 1434 | WP_023157970.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T291620 NZ_LR890624:1868674-1868776 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT291620 NZ_LR890624:c1868783-1868638 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT