Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1935626..1935771 | Replicon | chromosome |
| Accession | NZ_LR890600 | ||
| Organism | Klebsiella pneumoniae isolate INF122-sc-2279936 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1935662..1935764 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1935626..1935771 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMW81_RS09455 | 1931721..1932380 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| JMW81_RS09460 | 1932459..1932689 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| JMW81_RS09465 | 1932794..1933882 | + | 1089 | WP_201519980.1 | IS481 family transposase | - |
| JMW81_RS09470 | 1933901..1934275 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| JMW81_RS09475 | 1934279..1935148 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| JMW81_RS09480 | 1935165..1935503 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1935626..1935771 | - | 146 | - | - | Antitoxin |
| - | 1935662..1935764 | + | 103 | - | - | Toxin |
| JMW81_RS09485 | 1936139..1936282 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| JMW81_RS09490 | 1936387..1937355 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| JMW81_RS09495 | 1937512..1938165 | + | 654 | WP_009484457.1 | protein-serine/threonine phosphatase | - |
| JMW81_RS09500 | 1938162..1938353 | - | 192 | WP_002911395.1 | YebW family protein | - |
| JMW81_RS09505 | 1938451..1938690 | - | 240 | WP_002911393.1 | YebV family protein | - |
| JMW81_RS09510 | 1938806..1940239 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1915784..1940194 | 24410 | |
| - | flank | IS/Tn | - | - | 1932794..1933882 | 1088 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T291499 NZ_LR890600:1935662-1935764 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT291499 NZ_LR890600:c1935771-1935626 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
