Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1898166..1898311 Replicon chromosome
Accession NZ_LR890595
Organism Klebsiella pneumoniae isolate INF223-sc-2280103

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1898202..1898304 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1898166..1898311 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW78_RS09175 1893296..1895356 + 2061 WP_004151449.1 oligopeptidase B -
JMW78_RS09180 1895360..1896019 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW78_RS09185 1896098..1896328 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMW78_RS09190 1896441..1896815 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW78_RS09195 1896819..1897688 + 870 WP_201525268.1 copper homeostasis membrane protein CopD -
JMW78_RS09200 1897705..1898043 + 339 WP_002911404.1 YebY family protein -
- 1898166..1898311 - 146 - - Antitoxin
- 1898202..1898304 + 103 - - Toxin
JMW78_RS09205 1898679..1898822 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW78_RS09210 1898927..1899895 - 969 WP_181854232.1 VirK/YbjX family protein -
JMW78_RS09215 1900052..1900705 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
JMW78_RS09220 1900702..1900893 - 192 WP_002911395.1 YebW family protein -
JMW78_RS09225 1900991..1901230 - 240 WP_002911393.1 YebV family protein -
JMW78_RS09230 1901346..1902779 - 1434 WP_023157970.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291484 NZ_LR890595:1898202-1898304 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291484 NZ_LR890595:c1898311-1898166 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References