Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1901515..1901660 Replicon chromosome
Accession NZ_LR890564
Organism Klebsiella pneumoniae isolate KSB2_9A-sc-2280332

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1901551..1901653 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1901515..1901660 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW10_RS09205 1896645..1898705 + 2061 WP_004151449.1 oligopeptidase B -
JMW10_RS09210 1898709..1899368 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW10_RS09215 1899447..1899677 - 231 WP_040147502.1 DNA polymerase III subunit theta -
JMW10_RS09220 1899790..1900164 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW10_RS09225 1900168..1901037 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JMW10_RS09230 1901054..1901392 + 339 WP_002911404.1 YebY family protein -
- 1901515..1901660 - 146 - - Antitoxin
- 1901551..1901653 + 103 - - Toxin
JMW10_RS09235 1902028..1902171 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW10_RS09240 1902276..1903244 - 969 WP_004151446.1 VirK/YbjX family protein -
JMW10_RS09245 1903401..1904054 + 654 WP_032415192.1 protein-serine/threonine phosphatase -
JMW10_RS09250 1904051..1904242 - 192 WP_002911395.1 YebW family protein -
JMW10_RS09255 1904340..1904579 - 240 WP_002911393.1 YebV family protein -
JMW10_RS09260 1904695..1906128 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291423 NZ_LR890564:1901551-1901653 [Klebsiella pneumoniae]
GCAAGGCGGCTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291423 NZ_LR890564:c1901660-1901515 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGCCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References