Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1849685..1849830 Replicon chromosome
Accession NZ_LR890562
Organism Klebsiella pneumoniae isolate INF247-sc-2280148

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1849721..1849823 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1849685..1849830 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW77_RS09040 1844815..1846875 + 2061 WP_064189146.1 oligopeptidase B -
JMW77_RS09045 1846879..1847538 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW77_RS09050 1847617..1847847 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMW77_RS09055 1847960..1848334 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW77_RS09060 1848338..1849207 + 870 WP_064189145.1 copper homeostasis membrane protein CopD -
JMW77_RS09065 1849224..1849562 + 339 WP_002911404.1 YebY family protein -
- 1849685..1849830 - 146 - - Antitoxin
- 1849721..1849823 + 103 - - Toxin
JMW77_RS09070 1850198..1850341 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW77_RS09075 1850446..1851414 - 969 WP_073971755.1 VirK/YbjX family protein -
JMW77_RS09080 1851571..1852224 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
JMW77_RS09085 1852221..1852412 - 192 WP_002911395.1 YebW family protein -
JMW77_RS09090 1852510..1852749 - 240 WP_002911393.1 YebV family protein -
JMW77_RS09095 1852865..1854298 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291403 NZ_LR890562:1849721-1849823 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291403 NZ_LR890562:c1849830-1849685 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References