Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 522225..522370 Replicon chromosome
Accession NZ_LR890556
Organism Klebsiella pneumoniae isolate INF302-sc-2280090

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 522261..522363 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 522225..522370 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW84_RS02475 517355..519415 + 2061 WP_004151449.1 oligopeptidase B -
JMW84_RS02480 519419..520078 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW84_RS02485 520157..520387 - 231 WP_040147502.1 DNA polymerase III subunit theta -
JMW84_RS02490 520500..520874 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW84_RS02495 520878..521747 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JMW84_RS02500 521764..522102 + 339 WP_002911404.1 YebY family protein -
- 522225..522370 - 146 - - Antitoxin
- 522261..522363 + 103 - - Toxin
JMW84_RS02505 522738..522881 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW84_RS02510 522986..523954 - 969 WP_004151446.1 VirK/YbjX family protein -
JMW84_RS02515 524111..524764 + 654 WP_032415192.1 protein-serine/threonine phosphatase -
JMW84_RS02520 524761..524952 - 192 WP_002911395.1 YebW family protein -
JMW84_RS02525 525050..525289 - 240 WP_002911393.1 YebV family protein -
JMW84_RS02530 525405..526838 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291384 NZ_LR890556:522261-522363 [Klebsiella pneumoniae]
GCAAGGCGGCTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291384 NZ_LR890556:c522370-522225 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGCCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References