Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1932226..1932371 Replicon chromosome
Accession NZ_LR890547
Organism Klebsiella pneumoniae isolate INF142-sc-2279977

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1932262..1932364 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1932226..1932371 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX11_RS09285 1927356..1929416 + 2061 WP_004151449.1 oligopeptidase B -
JMX11_RS09290 1929420..1930079 - 660 WP_032425085.1 exodeoxyribonuclease X -
JMX11_RS09295 1930158..1930388 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX11_RS09300 1930501..1930875 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX11_RS09305 1930879..1931748 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMX11_RS09310 1931765..1932103 + 339 WP_016529031.1 YebY family protein -
- 1932226..1932371 - 146 - - Antitoxin
- 1932262..1932364 + 103 - - Toxin
JMX11_RS09315 1932739..1932882 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMX11_RS09320 1932987..1933955 - 969 WP_004151446.1 VirK/YbjX family protein -
JMX11_RS09325 1934112..1934765 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JMX11_RS09330 1934762..1934953 - 192 WP_002911395.1 YebW family protein -
JMX11_RS09335 1935051..1935290 - 240 WP_002911393.1 YebV family protein -
JMX11_RS09340 1935406..1936839 - 1434 WP_032411854.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291357 NZ_LR890547:1932262-1932364 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291357 NZ_LR890547:c1932371-1932226 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References