Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1858241..1858386 Replicon chromosome
Accession NZ_LR890542
Organism Klebsiella pneumoniae isolate INF319-sc-2280116

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1858277..1858379 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1858241..1858386 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX54_RS08900 1853371..1855431 + 2061 WP_004151449.1 oligopeptidase B -
JMX54_RS08905 1855435..1856094 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMX54_RS08910 1856173..1856403 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX54_RS08915 1856516..1856890 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX54_RS08920 1856894..1857763 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMX54_RS08925 1857780..1858118 + 339 WP_002911404.1 YebY family protein -
- 1858241..1858386 - 146 - - Antitoxin
- 1858277..1858379 + 103 - - Toxin
JMX54_RS08930 1858755..1858898 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMX54_RS08935 1859003..1859971 - 969 WP_004151446.1 VirK/YbjX family protein -
JMX54_RS08940 1860128..1860781 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
JMX54_RS08945 1860778..1860969 - 192 WP_002911395.1 YebW family protein -
JMX54_RS08950 1861067..1861306 - 240 WP_002911393.1 YebV family protein -
JMX54_RS08955 1861422..1862855 - 1434 WP_048988537.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291337 NZ_LR890542:1858277-1858379 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291337 NZ_LR890542:c1858386-1858241 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References