Detailed information of TA system TA029129

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3214149..3214802
• Replicon: chromosome
• Accession: NC_020547
• Organism: Acinetobacter baumannii D1279779

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: ABD1_RS15150
• Protein ID: WP_000607097.1
• Coordinates: 3214149..3214538 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: ABD1_RS15155
• Protein ID: WP_001288210.1
• Coordinates: 3214545..3214802 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ABD1_RS15135	3209267..3211462	-	2196	WP_001158905.1	TRAP transporter large permease subunit	-
ABD1_RS15140	3211650..3212216	-	567	WP_000651536.1	rhombosortase	-
ABD1_RS15145	3212294..3213379	-	1086	WP_000049106.1	hypothetical protein	-
ABD1_RS15150	3214149..3214538	-	390	WP_000607097.1	hypothetical protein	Toxin
ABD1_RS15155	3214545..3214802	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
ABD1_RS15160	3214990..3216162	+	1173	WP_001190546.1	acyl-CoA dehydrogenase family protein	-
ABD1_RS15165	3216212..3217702	-	1491	WP_000415133.1	NAD(P)/FAD-dependent oxidoreductase	-
ABD1_RS15170	3217884..3218261	-	378	WP_001216380.1	50S ribosomal protein L17	-
ABD1_RS15175	3218280..3219287	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15637.89 Da
• Isoelectric Point: 10.3890

>T29129 WP_000607097.1 NC_020547:c3214538-3214149 [Acinetobacter baumannii D1279779]
MINHSNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLVEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T29129 NC_020547:c3214538-3214149 [Acinetobacter baumannii D1279779]
TTGATCAACCATTCGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATCATTCACAGAACACCATT
TCTCGCGTCAAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGATTTATTTTGAAGGACATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGTAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT29129 WP_001288210.1 NC_020547:c3214802-3214545 [Acinetobacter baumannii D1279779]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT29129 NC_020547:c3214802-3214545 [Acinetobacter baumannii D1279779]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ATCCTGATTTACTCGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7