Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1865207..1865352 Replicon chromosome
Accession NZ_LR890527
Organism Klebsiella pneumoniae isolate INF361-sc-2280198

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1865243..1865345 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1865207..1865352 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW73_RS09125 1860337..1862397 + 2061 WP_004151449.1 oligopeptidase B -
JMW73_RS09130 1862401..1863060 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW73_RS09135 1863139..1863369 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMW73_RS09140 1863482..1863856 + 375 WP_201524362.1 CopC domain-containing protein YobA -
JMW73_RS09145 1863860..1864729 + 870 WP_104158933.1 copper homeostasis membrane protein CopD -
JMW73_RS09150 1864746..1865084 + 339 WP_016529031.1 YebY family protein -
- 1865207..1865352 - 146 - - Antitoxin
- 1865243..1865345 + 103 - - Toxin
JMW73_RS09155 1865722..1865862 - 141 Protein_1784 Ecr family regulatory small membrane protein -
JMW73_RS09160 1865967..1866935 - 969 WP_004151446.1 VirK/YbjX family protein -
JMW73_RS09165 1867092..1867745 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
JMW73_RS09170 1867742..1867933 - 192 WP_002911395.1 YebW family protein -
JMW73_RS09175 1868031..1868270 - 240 WP_002911393.1 YebV family protein -
JMW73_RS09180 1868386..1869819 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1811521..1869774 58253


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291285 NZ_LR890527:1865243-1865345 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291285 NZ_LR890527:c1865352-1865207 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References