Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1536581..1536726 Replicon chromosome
Accession NZ_LR890515
Organism Klebsiella pneumoniae isolate INF281-sc-2280206

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1536588..1536690 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1536581..1536726 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX78_RS07700 1532112..1533545 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
JMX78_RS07705 1533661..1533900 + 240 WP_002911393.1 YebV family protein -
JMX78_RS07710 1533998..1534189 + 192 WP_002911395.1 YebW family protein -
JMX78_RS07715 1534186..1534839 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
JMX78_RS07720 1534996..1535964 + 969 WP_004151446.1 VirK/YbjX family protein -
JMX78_RS07725 1536069..1536212 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1536581..1536726 + 146 - - Antitoxin
- 1536588..1536690 - 103 - - Toxin
JMX78_RS07730 1536849..1537187 - 339 WP_002911404.1 YebY family protein -
JMX78_RS07735 1537204..1538073 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JMX78_RS07740 1538077..1538451 - 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX78_RS07745 1538564..1538794 + 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX78_RS07750 1538873..1539532 + 660 WP_002911407.1 exodeoxyribonuclease X -
JMX78_RS07755 1539536..1541596 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1526697..1610878 84181


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291253 NZ_LR890515:c1536690-1536588 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291253 NZ_LR890515:1536581-1536726 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References