Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1887798..1887943 Replicon chromosome
Accession NZ_LR890493
Organism Klebsiella pneumoniae isolate INF018-sc-2279888

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1887834..1887936 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1887798..1887943 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMV82_RS09155 1882928..1884988 + 2061 WP_004151449.1 oligopeptidase B -
JMV82_RS09160 1884992..1885651 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMV82_RS09165 1885730..1885960 - 231 WP_040147502.1 DNA polymerase III subunit theta -
JMV82_RS09170 1886073..1886447 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMV82_RS09175 1886451..1887320 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JMV82_RS09180 1887337..1887675 + 339 WP_002911404.1 YebY family protein -
- 1887798..1887943 - 146 - - Antitoxin
- 1887834..1887936 + 103 - - Toxin
JMV82_RS09185 1888311..1888454 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMV82_RS09190 1888559..1889527 - 969 WP_004151446.1 VirK/YbjX family protein -
JMV82_RS09195 1889684..1890337 + 654 WP_032415192.1 protein-serine/threonine phosphatase -
JMV82_RS09200 1890334..1890525 - 192 WP_002911395.1 YebW family protein -
JMV82_RS09205 1890623..1890862 - 240 WP_002911393.1 YebV family protein -
JMV82_RS09210 1890978..1892411 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291188 NZ_LR890493:1887834-1887936 [Klebsiella pneumoniae]
GCAAGGCGGCTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291188 NZ_LR890493:c1887943-1887798 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGCCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References