Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2029051..2029196 Replicon chromosome
Accession NZ_LR890490
Organism Klebsiella pneumoniae isolate INF341-sc-2280155

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2029087..2029189 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2029051..2029196 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX00_RS09600 2024181..2026241 + 2061 WP_004151449.1 oligopeptidase B -
JMX00_RS09605 2026245..2026904 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMX00_RS09610 2026983..2027213 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX00_RS09615 2027326..2027700 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX00_RS09620 2027704..2028573 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMX00_RS09625 2028590..2028928 + 339 WP_181945946.1 YebY family protein -
- 2029051..2029196 - 146 - - Antitoxin
- 2029087..2029189 + 103 - - Toxin
JMX00_RS09630 2029563..2029706 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMX00_RS09635 2029811..2030779 - 969 WP_004151446.1 VirK/YbjX family protein -
JMX00_RS09640 2030936..2031589 + 654 WP_117078799.1 protein-serine/threonine phosphatase -
JMX00_RS09645 2031586..2031777 - 192 WP_002911395.1 YebW family protein -
JMX00_RS09650 2031875..2032114 - 240 WP_002911393.1 YebV family protein -
JMX00_RS09655 2032230..2033663 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291174 NZ_LR890490:2029087-2029189 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291174 NZ_LR890490:c2029196-2029051 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References