Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1995958..1996103 Replicon chromosome
Accession NZ_LR890464
Organism Klebsiella pneumoniae isolate INF079-sc-2280008

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1995994..1996096 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1995958..1996103 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW83_RS09385 1991088..1993148 + 2061 WP_004151449.1 oligopeptidase B -
JMW83_RS09390 1993152..1993811 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW83_RS09395 1993890..1994120 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMW83_RS09400 1994233..1994607 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW83_RS09405 1994611..1995480 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
JMW83_RS09410 1995497..1995835 + 339 WP_002911404.1 YebY family protein -
- 1995958..1996103 - 146 - - Antitoxin
- 1995994..1996096 + 103 - - Toxin
JMW83_RS09415 1996471..1996614 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW83_RS09420 1996719..1997687 - 969 WP_014907334.1 VirK/YbjX family protein -
JMW83_RS09425 1997844..1998497 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JMW83_RS09430 1998494..1998685 - 192 WP_002911395.1 YebW family protein -
JMW83_RS09435 1998783..1999022 - 240 WP_002911393.1 YebV family protein -
JMW83_RS09440 1999138..2000571 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291075 NZ_LR890464:1995994-1996096 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291075 NZ_LR890464:c1996103-1995958 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References