Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1824836..1824981 Replicon chromosome
Accession NZ_LR890456
Organism Klebsiella pneumoniae isolate INF032-sc-2279918

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1824872..1824974 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1824836..1824981 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMV68_RS08840 1819966..1822026 + 2061 WP_004151449.1 oligopeptidase B -
JMV68_RS08845 1822030..1822689 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMV68_RS08850 1822768..1822998 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMV68_RS08855 1823111..1823485 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMV68_RS08860 1823489..1824358 + 870 WP_064148102.1 copper homeostasis membrane protein CopD -
JMV68_RS08865 1824375..1824713 + 339 WP_002911404.1 YebY family protein -
- 1824836..1824981 - 146 - - Antitoxin
- 1824872..1824974 + 103 - - Toxin
JMV68_RS08870 1825350..1825493 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMV68_RS08875 1825598..1826566 - 969 WP_014907334.1 VirK/YbjX family protein -
JMV68_RS08880 1826723..1827376 + 654 WP_004175436.1 protein-serine/threonine phosphatase -
JMV68_RS08885 1827373..1827564 - 192 WP_002911395.1 YebW family protein -
JMV68_RS08890 1827662..1827901 - 240 WP_002911393.1 YebV family protein -
JMV68_RS08895 1828017..1829450 - 1434 WP_021440382.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291041 NZ_LR890456:1824872-1824974 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291041 NZ_LR890456:c1824981-1824836 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References