Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1536579..1536724 Replicon chromosome
Accession NZ_LR890426
Organism Klebsiella pneumoniae isolate INF298

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1536586..1536688 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1536579..1536724 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX68_RS07695 1532110..1533543 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
JMX68_RS07700 1533659..1533898 + 240 WP_002911393.1 YebV family protein -
JMX68_RS07705 1533996..1534187 + 192 WP_002911395.1 YebW family protein -
JMX68_RS07710 1534184..1534837 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
JMX68_RS07715 1534994..1535962 + 969 WP_004151446.1 VirK/YbjX family protein -
JMX68_RS07720 1536067..1536210 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1536579..1536724 + 146 - - Antitoxin
- 1536586..1536688 - 103 - - Toxin
JMX68_RS07725 1536847..1537185 - 339 WP_002911404.1 YebY family protein -
JMX68_RS07730 1537202..1538071 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JMX68_RS07735 1538075..1538449 - 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX68_RS07740 1538562..1538792 + 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX68_RS07745 1538871..1539530 + 660 WP_002911407.1 exodeoxyribonuclease X -
JMX68_RS07750 1539534..1541594 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1526695..1610876 84181


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290986 NZ_LR890426:c1536688-1536586 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290986 NZ_LR890426:1536579-1536724 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References