Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1939334..1939479 Replicon chromosome
Accession NZ_LR890424
Organism Klebsiella pneumoniae isolate INF331-sc-2280141

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1939370..1939472 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1939334..1939479 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX49_RS09280 1934464..1936524 + 2061 WP_004151449.1 oligopeptidase B -
JMX49_RS09285 1936528..1937187 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMX49_RS09290 1937266..1937496 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX49_RS09295 1937609..1937983 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX49_RS09300 1937987..1938856 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMX49_RS09305 1938873..1939211 + 339 WP_002911404.1 YebY family protein -
- 1939334..1939479 - 146 - - Antitoxin
- 1939370..1939472 + 103 - - Toxin
JMX49_RS09310 1939846..1939989 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMX49_RS09315 1940094..1941062 - 969 WP_004151446.1 VirK/YbjX family protein -
JMX49_RS09320 1941219..1941872 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
JMX49_RS09325 1941869..1942060 - 192 WP_002911395.1 YebW family protein -
JMX49_RS09330 1942158..1942397 - 240 WP_002911393.1 YebV family protein -
JMX49_RS09335 1942513..1943946 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290972 NZ_LR890424:1939370-1939472 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290972 NZ_LR890424:c1939479-1939334 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References