Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1949607..1949752 | Replicon | chromosome |
| Accession | NZ_LR890422 | ||
| Organism | Klebsiella pneumoniae isolate INF350-sc-2280174 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1949643..1949745 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1949607..1949752 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMW70_RS09310 | 1944737..1946797 | + | 2061 | WP_032419805.1 | oligopeptidase B | - |
| JMW70_RS09315 | 1946801..1947460 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| JMW70_RS09320 | 1947539..1947769 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| JMW70_RS09325 | 1947882..1948256 | + | 375 | WP_020316569.1 | CopC domain-containing protein YobA | - |
| JMW70_RS09330 | 1948260..1949129 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| JMW70_RS09335 | 1949146..1949484 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1949607..1949752 | - | 146 | - | - | Antitoxin |
| - | 1949643..1949745 | + | 103 | - | - | Toxin |
| JMW70_RS09340 | 1950120..1950263 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| JMW70_RS09345 | 1950368..1951336 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| JMW70_RS09350 | 1951493..1952146 | + | 654 | WP_009484457.1 | protein-serine/threonine phosphatase | - |
| JMW70_RS09355 | 1952143..1952334 | - | 192 | WP_002911395.1 | YebW family protein | - |
| JMW70_RS09360 | 1952432..1952671 | - | 240 | WP_002911393.1 | YebV family protein | - |
| JMW70_RS09365 | 1952787..1954220 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T290958 NZ_LR890422:1949643-1949745 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT290958 NZ_LR890422:c1949752-1949607 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
