Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1923451..1923596 Replicon chromosome
Accession NZ_LR890395
Organism Klebsiella pneumoniae isolate INF044-sc-2279940

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1923487..1923589 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1923451..1923596 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW67_RS09440 1918581..1920641 + 2061 WP_004151449.1 oligopeptidase B -
JMW67_RS09445 1920645..1921304 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW67_RS09450 1921383..1921613 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMW67_RS09455 1921726..1922100 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW67_RS09460 1922104..1922973 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMW67_RS09465 1922990..1923328 + 339 WP_002911404.1 YebY family protein -
- 1923451..1923596 - 146 - - Antitoxin
- 1923487..1923589 + 103 - - Toxin
JMW67_RS09470 1923965..1924108 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW67_RS09475 1924213..1925181 - 969 WP_073971755.1 VirK/YbjX family protein -
JMW67_RS09480 1925338..1925991 + 654 WP_032441330.1 protein-serine/threonine phosphatase -
JMW67_RS09485 1925988..1926179 - 192 WP_002911395.1 YebW family protein -
JMW67_RS09490 1926277..1926516 - 240 WP_002911393.1 YebV family protein -
JMW67_RS09495 1926632..1928065 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290869 NZ_LR890395:1923487-1923589 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290869 NZ_LR890395:c1923596-1923451 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References