Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1938462..1938607 Replicon chromosome
Accession NZ_LR890369
Organism Klebsiella pneumoniae isolate INF354-sc-2280183

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1938498..1938600 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1938462..1938607 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW41_RS09475 1933592..1935652 + 2061 WP_004151449.1 oligopeptidase B -
JMW41_RS09480 1935656..1936315 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW41_RS09485 1936394..1936624 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMW41_RS09490 1936737..1937111 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW41_RS09495 1937115..1937984 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMW41_RS09500 1938001..1938339 + 339 WP_002911404.1 YebY family protein -
- 1938462..1938607 - 146 - - Antitoxin
- 1938498..1938600 + 103 - - Toxin
JMW41_RS09505 1938975..1939118 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW41_RS09510 1939223..1940191 - 969 WP_014907334.1 VirK/YbjX family protein -
JMW41_RS09515 1940348..1941001 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
JMW41_RS09520 1940998..1941189 - 192 WP_002911395.1 YebW family protein -
JMW41_RS09525 1941287..1941526 - 240 WP_002911393.1 YebV family protein -
JMW41_RS09530 1941642..1943075 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290787 NZ_LR890369:1938498-1938600 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290787 NZ_LR890369:c1938607-1938462 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References