Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1829441..1829586 | Replicon | chromosome |
| Accession | NZ_LR890360 | ||
| Organism | Klebsiella pneumoniae isolate INF049-sc-2279950 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1829477..1829579 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1829441..1829586 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMW75_RS08840 | 1824571..1826631 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| JMW75_RS08845 | 1826635..1827294 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| JMW75_RS08850 | 1827373..1827603 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| JMW75_RS08855 | 1827716..1828090 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| JMW75_RS08860 | 1828094..1828963 | + | 870 | WP_009307538.1 | copper homeostasis membrane protein CopD | - |
| JMW75_RS08865 | 1828980..1829318 | + | 339 | WP_009307539.1 | YebY family protein | - |
| - | 1829441..1829586 | - | 146 | - | - | Antitoxin |
| - | 1829477..1829579 | + | 103 | - | - | Toxin |
| JMW75_RS08870 | 1829955..1830098 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| JMW75_RS08875 | 1830226..1831272 | - | 1047 | WP_201519724.1 | IS481 family transposase | - |
| JMW75_RS08880 | 1831331..1832272 | - | 942 | Protein_1730 | DUF535 domain-containing protein | - |
| JMW75_RS08885 | 1832429..1833082 | + | 654 | WP_009307541.1 | protein-serine/threonine phosphatase | - |
| JMW75_RS08890 | 1833079..1833270 | - | 192 | WP_002911395.1 | YebW family protein | - |
| JMW75_RS08895 | 1833368..1833607 | - | 240 | WP_002911393.1 | YebV family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1824604..1835111 | 10507 | |
| - | flank | IS/Tn | - | - | 1830226..1830723 | 497 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T290765 NZ_LR890360:1829477-1829579 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT290765 NZ_LR890360:c1829586-1829441 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
