Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1992413..1992558 Replicon chromosome
Accession NZ_LR890356
Organism Klebsiella pneumoniae isolate INF231-sc-2280121

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1992449..1992551 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1992413..1992558 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMV88_RS09660 1987543..1989603 + 2061 WP_004148850.1 oligopeptidase B -
JMV88_RS09665 1989607..1990266 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMV88_RS09670 1990345..1990575 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMV88_RS09675 1990688..1991062 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMV88_RS09680 1991066..1991935 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
JMV88_RS09685 1991952..1992290 + 339 WP_002911404.1 YebY family protein -
- 1992413..1992558 - 146 - - Antitoxin
- 1992449..1992551 + 103 - - Toxin
JMV88_RS09690 1992926..1993069 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMV88_RS09695 1993174..1994142 - 969 WP_014907334.1 VirK/YbjX family protein -
JMV88_RS09700 1994299..1994952 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
JMV88_RS09705 1994949..1995140 - 192 WP_002911395.1 YebW family protein -
JMV88_RS09710 1995238..1995477 - 240 WP_002911393.1 YebV family protein -
JMV88_RS09715 1995593..1997026 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290749 NZ_LR890356:1992449-1992551 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290749 NZ_LR890356:c1992558-1992413 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References