290697

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-GNAT
Location 4029394..4030214 Replicon chromosome
Accession NZ_LR890334
Organism Escherichia coli isolate MINF_9A-sc-2280436

Toxin (Protein)


Gene name yjhX Uniprot ID B6I030
Locus tag JMW07_RS19365 Protein ID WP_001054379.1
Coordinates 4029957..4030214 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag JMW07_RS19360 Protein ID WP_000123957.1
Coordinates 4029394..4029945 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW07_RS19330 4025088..4026401 - 1314 WP_000460845.1 galactitol-specific PTS transporter subunit IIC -
JMW07_RS19335 4026413..4026691 - 279 WP_000722973.1 PTS sugar transporter subunit IIB -
JMW07_RS19340 4026688..4027809 - 1122 WP_000010833.1 M42 family metallopeptidase -
JMW07_RS19345 4028054..4028170 - 117 Protein_3777 VOC family protein -
JMW07_RS19350 4028208..4028468 - 261 WP_000077645.1 hypothetical protein -
JMW07_RS19355 4028596..4029342 - 747 WP_000354249.1 class I SAM-dependent methyltransferase -
JMW07_RS19360 4029394..4029945 - 552 WP_000123957.1 N-acetyltransferase Antitoxin
JMW07_RS19365 4029957..4030214 - 258 WP_001054379.1 YjhX family toxin Toxin
JMW07_RS19370 4030591..4030767 - 177 Protein_3782 GNAT family N-acetyltransferase -
JMW07_RS19375 4030753..4031850 + 1098 Protein_3783 DNA helicase -
JMW07_RS19380 4032433..4033413 - 981 WP_000991462.1 9-O-acetyl-N-acetylneuraminic acid deacetylase -
JMW07_RS19385 4033477..4034583 - 1107 WP_001295733.1 N-acetylneuraminate epimerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(19-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9568.07 Da        Isoelectric Point: 11.1381

>T290697 WP_001054379.1 NZ_LR890334:c4030214-4029957 [Escherichia coli]
MNLSRQEQRTLHVLAKGGRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20358.34 Da        Isoelectric Point: 6.4182

>AT290697 WP_000123957.1 NZ_LR890334:c4029945-4029394 [Escherichia coli]
MTAHHFTFQITDESDASDIREVETRAFGFSKEADLTASLLEDESARPALSLLARHEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQALTA
QPMNVTGHIQCAQALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB B6I030

Antitoxin

Source ID Structure

References