Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/- |
Location | 4614960..4615603 | Replicon | chromosome |
Accession | NZ_LR890326 | ||
Organism | Escherichia coli isolate MINF_1A-sc-2280431 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | - |
Locus tag | JMV91_RS22535 | Protein ID | WP_049038273.1 |
Coordinates | 4615316..4615603 (-) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | U9Y7E1 |
Locus tag | JMV91_RS22530 | Protein ID | WP_000593555.1 |
Coordinates | 4614960..4615319 (-) | Length | 120 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JMV91_RS22500 | 4610075..4610548 | + | 474 | WP_012311717.1 | PTS sugar transporter subunit IIA | - |
JMV91_RS22505 | 4610545..4610826 | + | 282 | WP_000084021.1 | PTS sugar transporter subunit IIB | - |
JMV91_RS22510 | 4610900..4612258 | + | 1359 | WP_001302220.1 | PTS galactitol transporter subunit IIC | - |
JMV91_RS22515 | 4612251..4613759 | + | 1509 | WP_012311797.1 | carbohydrate kinase | - |
JMV91_RS22520 | 4613749..4614018 | + | 270 | WP_000949581.1 | HPr family phosphocarrier protein | - |
JMV91_RS22525 | 4614050..4614910 | + | 861 | WP_001131792.1 | class II aldolase | - |
JMV91_RS22530 | 4614960..4615319 | - | 360 | WP_000593555.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
JMV91_RS22535 | 4615316..4615603 | - | 288 | WP_049038273.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
JMV91_RS22540 | 4615663..4616787 | - | 1125 | WP_001314210.1 | ABC transporter permease | - |
JMV91_RS22545 | 4616787..4619522 | - | 2736 | WP_000149118.1 | ribosome-associated ATPase/putative transporter RbbA | - |
JMV91_RS22550 | 4619519..4620586 | - | 1068 | WP_000361481.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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