Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1856459..1856604 Replicon chromosome
Accession NZ_LR890323
Organism Klebsiella pneumoniae isolate INF348-sc-2280170

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1856495..1856597 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1856459..1856604 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW45_RS09075 1851589..1853649 + 2061 WP_004151449.1 oligopeptidase B -
JMW45_RS09080 1853653..1854312 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW45_RS09085 1854391..1854621 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMW45_RS09090 1854734..1855108 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW45_RS09095 1855112..1855981 + 870 WP_201522393.1 copper homeostasis membrane protein CopD -
JMW45_RS09100 1855998..1856336 + 339 WP_002911404.1 YebY family protein -
- 1856459..1856604 - 146 - - Antitoxin
- 1856495..1856597 + 103 - - Toxin
JMW45_RS09105 1856973..1857116 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW45_RS09110 1857221..1858189 - 969 WP_004151446.1 VirK/YbjX family protein -
JMW45_RS09115 1858346..1858999 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
JMW45_RS09120 1858996..1859187 - 192 WP_002911395.1 YebW family protein -
JMW45_RS09125 1859285..1859524 - 240 WP_032426373.1 YebV family protein -
JMW45_RS09130 1859640..1861073 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290636 NZ_LR890323:1856495-1856597 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290636 NZ_LR890323:c1856604-1856459 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References