290611

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 5138270..5138928 Replicon chromosome
Accession NZ_LR890312
Organism Klebsiella oxytoca isolate MSB1_10D-sc-2280340

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag JMX52_RS23945 Protein ID WP_201621101.1
Coordinates 5138270..5138590 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag JMX52_RS23950 Protein ID WP_201621102.1
Coordinates 5138611..5138928 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX52_RS23925 5134514..5135218 + 705 WP_032726119.1 DNA/RNA non-specific endonuclease -
JMX52_RS23930 5135507..5135830 + 324 WP_023320260.1 endoribonuclease SymE -
JMX52_RS23935 5135977..5136411 + 435 WP_023320259.1 VOC family protein -
JMX52_RS23940 5137029..5138162 + 1134 WP_201621100.1 hypothetical protein -
JMX52_RS23945 5138270..5138590 - 321 WP_201621101.1 TA system toxin CbtA family protein Toxin
JMX52_RS23950 5138611..5138928 - 318 WP_201621102.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
JMX52_RS23955 5138946..5139167 - 222 WP_110123787.1 DUF987 domain-containing protein -
JMX52_RS23960 5139176..5139658 - 483 WP_201621103.1 DNA repair protein RadC -
JMX52_RS23965 5139667..5140125 - 459 WP_201621104.1 antirestriction protein -
JMX52_RS23970 5140212..5140448 - 237 WP_201621105.1 DUF905 domain-containing protein -
JMX52_RS23975 5140526..5140936 - 411 WP_201621106.1 hypothetical protein -
JMX52_RS23980 5141003..5141440 - 438 WP_201621107.1 hypothetical protein -
JMX52_RS23985 5141482..5142018 - 537 WP_201621108.1 DUF4339 domain-containing protein -
JMX52_RS23990 5142044..5142754 - 711 WP_201621109.1 transcriptional regulator -
JMX52_RS23995 5142963..5143787 - 825 WP_201621110.1 DUF945 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 5135507..5167957 32450


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-102)

Antitoxin

Antitoxin CbeA

(4-104)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12034.78 Da        Isoelectric Point: 6.4564

>T290611 WP_201621101.1 NZ_LR890312:c5138590-5138270 [Klebsiella oxytoca]
MKNLPATVSRATKPCLSPVAVWQMLLTRLLEQHYGLTLNDTPFSDETVIKEHIDAGITLTDAVNFLVDKYELVRTDRRGF
SWQEQSPYLQVVDILWARQAIGSSSK

Download         Length: 321 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11776.36 Da        Isoelectric Point: 6.3096

>AT290611 WP_201621102.1 NZ_LR890312:c5138928-5138611 [Klebsiella oxytoca]
MSNPTWGLQRDITPCLGARLVQEGNRLHYLADRASFTGTFSEAECLKLDVAFPHFISQMESMLTTGEMNPRHAHCVTLYH
NGFTCEADTLGSCGYVYIAIYPTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References