Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX(toxin)
Location 4619787..4620606 Replicon chromosome
Accession NZ_LR890312
Organism Klebsiella oxytoca isolate MSB1_10D-sc-2280340

Toxin (Protein)


Gene name yjhX Uniprot ID J5WT09
Locus tag JMX52_RS21610 Protein ID WP_004110819.1
Coordinates 4620349..4620606 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag JMX52_RS21605 Protein ID WP_016809596.1
Coordinates 4619787..4620338 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX52_RS21590 4615637..4616914 + 1278 WP_024273764.1 hypothetical protein -
JMX52_RS21595 4616932..4618095 + 1164 WP_024273763.1 MFS transporter -
JMX52_RS21600 4618141..4619769 - 1629 WP_032727844.1 SAM-dependent methyltransferase -
JMX52_RS21605 4619787..4620338 - 552 WP_016809596.1 N-acetyltransferase Antitoxin
JMX52_RS21610 4620349..4620606 - 258 WP_004110819.1 YjhX family toxin Toxin
JMX52_RS21615 4621188..4622372 + 1185 WP_004099225.1 mannonate dehydratase -
JMX52_RS21620 4622447..4623922 + 1476 WP_004110817.1 fructuronate reductase -
JMX52_RS21625 4624058..4624834 + 777 WP_004099223.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(17-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9552.07 Da        Isoelectric Point: 11.1381

>T290610 WP_004110819.1 NZ_LR890312:c4620606-4620349 [Klebsiella oxytoca]
MNLSRQEQRTLHVLAKGGRIAHIRDASGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20169.01 Da        Isoelectric Point: 6.8799

>AT290610 WP_016809596.1 NZ_LR890312:c4620338-4619787 [Klebsiella oxytoca]
MTNHNFTFHITSERDADDIREVETRAFGFSKEADLVAALLNDESAHPSLSLLAKHNGKAVGHILFTLATFKGESDSPMMH
ILAPLAVVPEYQGVGVGGLLIQRGIEHLKAAGSEAVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMLQRLSS
RPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H3H6Y2

Antitoxin

Source ID Structure

References