Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1879864..1880009 Replicon chromosome
Accession NZ_LR890307
Organism Klebsiella pneumoniae isolate INF188-sc-2280054

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1879900..1880002 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1879864..1880009 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW12_RS09170 1874994..1877054 + 2061 WP_004151449.1 oligopeptidase B -
JMW12_RS09175 1877058..1877717 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW12_RS09180 1877796..1878026 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMW12_RS09185 1878139..1878513 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW12_RS09190 1878517..1879386 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JMW12_RS09195 1879403..1879741 + 339 WP_002911404.1 YebY family protein -
- 1879864..1880009 - 146 - - Antitoxin
- 1879900..1880002 + 103 - - Toxin
JMW12_RS09200 1880377..1880520 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW12_RS09205 1880625..1881593 - 969 WP_074195444.1 DUF535 family protein -
JMW12_RS09210 1881750..1882403 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JMW12_RS09215 1882400..1882591 - 192 WP_002911395.1 YebW family protein -
JMW12_RS09220 1882689..1882928 - 240 WP_002911393.1 YebV family protein -
JMW12_RS09225 1883044..1884477 - 1434 WP_064190786.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290591 NZ_LR890307:1879900-1880002 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290591 NZ_LR890307:c1880009-1879864 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References