Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1871373..1871518 Replicon chromosome
Accession NZ_LR890291
Organism Klebsiella pneumoniae strain KSB1_1B

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1871409..1871511 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1871373..1871518 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW65_RS09135 1866503..1868563 + 2061 WP_004151449.1 oligopeptidase B -
JMW65_RS09140 1868567..1869226 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW65_RS09145 1869305..1869535 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMW65_RS09150 1869648..1870022 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW65_RS09155 1870026..1870895 + 870 WP_094644986.1 copper homeostasis membrane protein CopD -
JMW65_RS09160 1870912..1871250 + 339 WP_002911404.1 YebY family protein -
- 1871373..1871518 - 146 - - Antitoxin
- 1871409..1871511 + 103 - - Toxin
JMW65_RS09165 1871886..1872029 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW65_RS09170 1872134..1873102 - 969 WP_074181864.1 VirK/YbjX family protein -
JMW65_RS09175 1873259..1873912 + 654 WP_004175436.1 protein-serine/threonine phosphatase -
JMW65_RS09180 1873909..1874100 - 192 WP_002911395.1 YebW family protein -
JMW65_RS09185 1874198..1874437 - 240 WP_002911393.1 YebV family protein -
JMW65_RS09190 1874553..1875986 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290533 NZ_LR890291:1871409-1871511 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290533 NZ_LR890291:c1871518-1871373 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References