Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1792042..1792187 Replicon chromosome
Accession NZ_LR890286
Organism Klebsiella pneumoniae isolate INF156-sc-2280002

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1792078..1792180 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1792042..1792187 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMV92_RS08655 1787172..1789232 + 2061 WP_004151449.1 oligopeptidase B -
JMV92_RS08660 1789236..1789895 - 660 WP_021440386.1 exodeoxyribonuclease X -
JMV92_RS08665 1789974..1790204 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMV92_RS08670 1790317..1790691 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMV92_RS08675 1790695..1791564 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
JMV92_RS08680 1791581..1791919 + 339 WP_002911404.1 YebY family protein -
- 1792042..1792187 - 146 - - Antitoxin
- 1792078..1792180 + 103 - - Toxin
JMV92_RS08685 1792555..1792698 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMV92_RS08690 1792803..1793771 - 969 WP_004151446.1 VirK/YbjX family protein -
JMV92_RS08695 1793928..1794581 + 654 WP_004175436.1 protein-serine/threonine phosphatase -
JMV92_RS08700 1794578..1794769 - 192 WP_002911395.1 YebW family protein -
JMV92_RS08705 1794867..1795106 - 240 WP_002911393.1 YebV family protein -
JMV92_RS08710 1795222..1796655 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290482 NZ_LR890286:1792078-1792180 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290482 NZ_LR890286:c1792187-1792042 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References