Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1865052..1865197 Replicon chromosome
Accession NZ_LR890277
Organism Klebsiella pneumoniae isolate INF355-sc-2280185

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1865088..1865190 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1865052..1865197 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMV94_RS09120 1860182..1862242 + 2061 WP_004151449.1 oligopeptidase B -
JMV94_RS09125 1862246..1862905 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMV94_RS09130 1862984..1863214 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMV94_RS09135 1863327..1863701 + 375 WP_201524362.1 CopC domain-containing protein YobA -
JMV94_RS09140 1863705..1864574 + 870 WP_104158933.1 copper homeostasis membrane protein CopD -
JMV94_RS09145 1864591..1864929 + 339 WP_016529031.1 YebY family protein -
- 1865052..1865197 - 146 - - Antitoxin
- 1865088..1865190 + 103 - - Toxin
JMV94_RS09150 1865567..1865707 - 141 Protein_1784 Ecr family regulatory small membrane protein -
JMV94_RS09155 1865812..1866780 - 969 WP_004151446.1 VirK/YbjX family protein -
JMV94_RS09160 1866937..1867590 + 654 WP_020802220.1 protein-serine/threonine phosphatase -
JMV94_RS09165 1867587..1867778 - 192 WP_002911395.1 YebW family protein -
JMV94_RS09170 1867876..1868115 - 240 WP_002911393.1 YebV family protein -
JMV94_RS09175 1868231..1869664 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1811366..1869619 58253


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290464 NZ_LR890277:1865088-1865190 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290464 NZ_LR890277:c1865197-1865052 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References