Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1886557..1886702 Replicon chromosome
Accession NZ_LR890240
Organism Klebsiella pneumoniae isolate INF329-sc-2280137

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1886593..1886695 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1886557..1886702 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMV78_RS09120 1881687..1883747 + 2061 WP_004151449.1 oligopeptidase B -
JMV78_RS09125 1883751..1884410 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMV78_RS09130 1884489..1884719 - 231 WP_040147502.1 DNA polymerase III subunit theta -
JMV78_RS09135 1884832..1885206 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMV78_RS09140 1885210..1886079 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JMV78_RS09145 1886096..1886434 + 339 WP_002911404.1 YebY family protein -
- 1886557..1886702 - 146 - - Antitoxin
- 1886593..1886695 + 103 - - Toxin
JMV78_RS09150 1887070..1887213 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMV78_RS09155 1887318..1888286 - 969 WP_004151446.1 VirK/YbjX family protein -
JMV78_RS09160 1888443..1889096 + 654 WP_032415192.1 protein-serine/threonine phosphatase -
JMV78_RS09165 1889093..1889284 - 192 WP_002911395.1 YebW family protein -
JMV78_RS09170 1889382..1889621 - 240 WP_002911393.1 YebV family protein -
JMV78_RS09175 1889737..1891170 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290375 NZ_LR890240:1886593-1886695 [Klebsiella pneumoniae]
GCAAGGCGGCTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290375 NZ_LR890240:c1886702-1886557 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGCCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References