Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1884876..1885021 Replicon chromosome
Accession NZ_LR890230
Organism Klebsiella pneumoniae isolate KSB1_6J

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1884912..1885014 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1884876..1885021 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW15_RS09115 1880006..1882066 + 2061 WP_004151449.1 oligopeptidase B -
JMW15_RS09120 1882070..1882729 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW15_RS09125 1882808..1883038 - 231 WP_040147502.1 DNA polymerase III subunit theta -
JMW15_RS09130 1883151..1883525 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW15_RS09135 1883529..1884398 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
JMW15_RS09140 1884415..1884753 + 339 WP_002911404.1 YebY family protein -
- 1884876..1885021 - 146 - - Antitoxin
- 1884912..1885014 + 103 - - Toxin
JMW15_RS09145 1885389..1885532 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW15_RS09150 1885637..1886605 - 969 WP_004151446.1 VirK/YbjX family protein -
JMW15_RS09155 1886762..1887415 + 654 WP_032415192.1 protein-serine/threonine phosphatase -
JMW15_RS09160 1887412..1887603 - 192 WP_002911395.1 YebW family protein -
JMW15_RS09165 1887701..1887940 - 240 WP_002911393.1 YebV family protein -
JMW15_RS09170 1888056..1889489 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290344 NZ_LR890230:1884912-1885014 [Klebsiella pneumoniae]
GCAAGGCGGCTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290344 NZ_LR890230:c1885021-1884876 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGCCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References