Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1905691..1905836 Replicon chromosome
Accession NZ_LR890217
Organism Klebsiella pneumoniae isolate INF357-sc-2280189

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1905727..1905829 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1905691..1905836 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMV73_RS09350 1900821..1902881 + 2061 WP_004151449.1 oligopeptidase B -
JMV73_RS09355 1902885..1903544 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMV73_RS09360 1903623..1903853 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMV73_RS09365 1903966..1904340 + 375 WP_048279882.1 CopC domain-containing protein YobA -
JMV73_RS09370 1904344..1905213 + 870 WP_048279880.1 copper homeostasis membrane protein CopD -
JMV73_RS09375 1905230..1905568 + 339 WP_002911404.1 YebY family protein -
- 1905691..1905836 - 146 - - Antitoxin
- 1905727..1905829 + 103 - - Toxin
JMV73_RS09380 1906204..1906347 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMV73_RS09385 1906452..1907420 - 969 WP_004151446.1 VirK/YbjX family protein -
JMV73_RS09390 1907577..1908230 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
JMV73_RS09395 1908227..1908418 - 192 WP_002911395.1 YebW family protein -
JMV73_RS09400 1908516..1908755 - 240 WP_002911393.1 YebV family protein -
JMV73_RS09405 1908871..1910304 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290327 NZ_LR890217:1905727-1905829 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290327 NZ_LR890217:c1905836-1905691 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References