Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 4873257..4874938 Replicon chromosome
Accession NZ_LR890209
Organism Klebsiella pneumoniae isolate INF022-sc-2279895

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag JMW18_RS23815 Protein ID WP_022065798.1
Coordinates 4873257..4874174 (-) Length 306 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag JMW18_RS23820 Protein ID WP_039102729.1
Coordinates 4874180..4874938 (-) Length 253 a.a.

Genomic Context


JMW18_RS23795JMW18_RS23800JMW18_RS23805JMW18_RS23810JMW18_RS23830JMW18_RS23835JMW18_RS23815JMW18_RS23820JMW18_RS23825
Location: 4868563..4870083 (1521 bp)
Type: Others
Protein ID: WP_094955305.1
Location: 4870080..4871078 (999 bp)
Type: Others
Protein ID: WP_049162519.1
Location: 4871109..4872050 (942 bp)
Type: Others
Protein ID: WP_012543155.1
Location: 4872125..4873132 (1008 bp)
Type: Others
Protein ID: WP_023339423.1
Location: 4876024..4878171 (2148 bp)
Type: Others
Protein ID: WP_012543160.1
Location: 4878877..4879563 (687 bp)
Type: Others
Protein ID: WP_008807260.1
Location: 4873257..4874174 (918 bp)
Type: Toxin
Protein ID: WP_022065798.1
Location: 4874180..4874938 (759 bp)
Type: Antitoxin
Protein ID: WP_039102729.1
Location: 4875023..4875751 (729 bp)
Type: Others
Protein ID: WP_008807258.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JMW18_RS237954868563..4870083+1521WP_094955305.1sugar ABC transporter ATP-binding protein-
JMW18_RS238004870080..4871078+999WP_049162519.1COG4158 family protein-
JMW18_RS238054871109..4872050+942WP_012543155.1ABC transporter substrate-binding protein-
JMW18_RS238104872125..4873132+1008WP_023339423.1carbohydrate kinase family protein-
JMW18_RS238154873257..4874174-918WP_022065798.1nucleotidyl transferase AbiEii/AbiGii toxin family proteinToxin
JMW18_RS238204874180..4874938-759WP_039102729.1type IV toxin-antitoxin system AbiEi family antitoxinAntitoxin
JMW18_RS238254875023..4875751-729WP_008807258.1response regulator transcription factor-
JMW18_RS238304876024..4878171+2148WP_012543160.1formate dehydrogenase H subunit alpha, selenocysteine-containing-
JMW18_RS238354878877..4879563+687WP_008807260.1sel1 repeat family protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 306 a.a.        Molecular weight: 34751.14 Da        Isoelectric Point: 5.4707

>T290317 WP_022065798.1 NZ_LR890209:c4874174-4873257 [Klebsiella pneumoniae]
MDIQAPYYRQVALLMQVLPYVAVEREFALKGGTAINLFIRDFPRLSVDIDLAWVPLESRTIALPHIRDALARIAANLQQQ
AGMNAVLQANRSDEMRVVVTTDSAQIKIEVSPVARGTLYPPQEREVVGAVEDVFGYASLPVVSLPDLYGGKLCAALDRQH
PRDFYDVKLLLDAQELNRPIFNGFIAYLLSHNRPLAEVLSPRWKDIAEPFYREFSGMTFETIALEELTAVPYRMIDALKS
CFTQQDIDFLLSFKRGEPDWRLAPETRIQDLPAVQWKLRNIHQMPAIKRAESLDKLEKVLAEWRS

Download         Length: 918 bp


Antitoxin


Download         Length: 253 a.a.        Molecular weight: 28642.97 Da        Isoelectric Point: 10.1988

>AT290317 WP_039102729.1 NZ_LR890209:c4874938-4874180 [Klebsiella pneumoniae]
MSSKLNWLLQNSAPGDVILQSWLSRHAISPSLAFKYTQSGWLKKRGNGVYARAGREPEWNDALACLQNQLAAPVYVAGLS
SLVWQGRSHYLQLKQNQCWLSMENKALLPKWFREFPGVEWIVISGQKLPVLDDKYRVTLDVKGKRLTGSAPELAAYELLS
AVPGTLSFNHAAELFQGLVNLNPRKVEYLLSVSQSVQTKRLYLFFASFYEHGWLRRIDSQKIDLGAGKRQIVVNGKFNAQ
YQITVPERFQKE

Download         Length: 759 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References