Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1869848..1869993 Replicon chromosome
Accession NZ_LR890209
Organism Klebsiella pneumoniae isolate INF022-sc-2279895

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1869884..1869986 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1869848..1869993 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMW18_RS09120 1864978..1867038 + 2061 WP_004151449.1 oligopeptidase B -
JMW18_RS09125 1867042..1867701 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMW18_RS09130 1867780..1868010 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMW18_RS09135 1868123..1868497 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMW18_RS09140 1868501..1869370 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMW18_RS09145 1869387..1869725 + 339 WP_016529031.1 YebY family protein -
- 1869848..1869993 - 146 - - Antitoxin
- 1869884..1869986 + 103 - - Toxin
JMW18_RS09150 1870361..1870504 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMW18_RS09155 1870610..1871578 - 969 WP_201519514.1 VirK/YbjX family protein -
JMW18_RS09160 1871735..1872388 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JMW18_RS09165 1872385..1872576 - 192 WP_002911395.1 YebW family protein -
JMW18_RS09170 1872674..1872913 - 240 WP_002911393.1 YebV family protein -
JMW18_RS09175 1872979..1874460 - 1482 WP_201519515.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290311 NZ_LR890209:1869884-1869986 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290311 NZ_LR890209:c1869993-1869848 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References