Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 551839..551984 Replicon chromosome
Accession NZ_LR890202
Organism Klebsiella pneumoniae isolate INF008-sc-2279879

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 551875..551977 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 551839..551984 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMV80_RS02605 546969..549029 + 2061 WP_004151449.1 oligopeptidase B -
JMV80_RS02610 549033..549692 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMV80_RS02615 549771..550001 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMV80_RS02620 550114..550488 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMV80_RS02625 550492..551361 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMV80_RS02630 551378..551716 + 339 WP_002911404.1 YebY family protein -
- 551839..551984 - 146 - - Antitoxin
- 551875..551977 + 103 - - Toxin
JMV80_RS02635 552352..552495 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMV80_RS02640 552600..553568 - 969 WP_004151446.1 VirK/YbjX family protein -
JMV80_RS02645 553725..554378 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JMV80_RS02650 554375..554566 - 192 WP_002911395.1 YebW family protein -
JMV80_RS02655 554664..554903 - 240 WP_002911393.1 YebV family protein -
JMV80_RS02660 555019..556452 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290276 NZ_LR890202:551875-551977 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290276 NZ_LR890202:c551984-551839 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References