Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2283308..2283576 Replicon chromosome
Accession NZ_LR890198
Organism Escherichia coli isolate MINF_1D-sc-2280456

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2283436..2283538 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2283308..2283576 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMV89_RS10645 2279862..2280524 - 663 WP_000944256.1 exodeoxyribonuclease X -
JMV89_RS10650 2280547..2281203 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
JMV89_RS10655 2281305..2281535 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JMV89_RS10660 2281674..2282048 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JMV89_RS10665 2282052..2282924 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
JMV89_RS10670 2282937..2283278 + 342 WP_000976472.1 YebY family protein -
- 2283308..2283576 - 269 - - Antitoxin
- 2283436..2283538 + 103 - - Toxin
JMV89_RS10675 2283673..2284329 + 657 WP_000812742.1 protein-serine/threonine phosphatase -
JMV89_RS10680 2284330..2284521 - 192 WP_001317886.1 YebW family protein -
JMV89_RS10685 2284626..2284862 - 237 WP_001295499.1 DUF1480 family protein -
JMV89_RS10690 2284980..2286419 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290248 NZ_LR890198:2283436-2283538 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT290248 NZ_LR890198:c2283576-2283308 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References