Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1957397..1957542 Replicon chromosome
Accession NZ_LR890185
Organism Klebsiella pneumoniae isolate INF072-sc-2279995

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1957433..1957535 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1957397..1957542 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMV85_RS09585 1952527..1954587 + 2061 WP_004151449.1 oligopeptidase B -
JMV85_RS09590 1954591..1955250 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMV85_RS09595 1955329..1955559 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMV85_RS09600 1955672..1956046 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMV85_RS09605 1956050..1956919 + 870 WP_023316211.1 copper homeostasis membrane protein CopD -
JMV85_RS09610 1956936..1957274 + 339 WP_002911404.1 YebY family protein -
- 1957397..1957542 - 146 - - Antitoxin
- 1957433..1957535 + 103 - - Toxin
JMV85_RS09615 1957910..1958053 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMV85_RS09620 1958158..1959126 - 969 WP_004151446.1 VirK/YbjX family protein -
JMV85_RS09625 1959283..1959936 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
JMV85_RS09630 1959933..1960124 - 192 WP_002911395.1 YebW family protein -
JMV85_RS09635 1960222..1960461 - 240 WP_002911393.1 YebV family protein -
JMV85_RS09640 1960577..1962010 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290212 NZ_LR890185:1957433-1957535 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290212 NZ_LR890185:c1957542-1957397 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References