Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 258312..258583 Replicon chromosome
Accession NZ_LR883965
Organism Escherichia coli isolate 2016-17-550

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 258442..258545 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 258312..258583 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMV10_RS01270 254867..255529 - 663 WP_000944256.1 exodeoxyribonuclease X -
JMV10_RS01275 255553..256209 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
JMV10_RS01280 256311..256541 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JMV10_RS01285 256680..257054 + 375 WP_000204699.1 CopC domain-containing protein YobA -
JMV10_RS01290 257058..257930 + 873 WP_000879285.1 copper homeostasis membrane protein CopD -
JMV10_RS01295 257943..258284 + 342 WP_000976492.1 YebY family protein -
- 258312..258583 - 272 - - Antitoxin
- 258442..258545 + 104 - - Toxin
JMV10_RS01300 258680..259336 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
JMV10_RS01305 259337..259528 - 192 WP_001296140.1 YebW family protein -
JMV10_RS01310 259633..259869 - 237 WP_001295499.1 DUF1480 family protein -
JMV10_RS01315 259987..261426 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T290166 NZ_LR883965:258442-258545 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT290166 NZ_LR883965:c258583-258312 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References