Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2099407..2099678 Replicon chromosome
Accession NZ_LR883012
Organism Escherichia coli isolate L4_E1441_ETEC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2099537..2099640 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2099407..2099678 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLZ95_RS10085 2095962..2096624 - 663 WP_000944258.1 exodeoxyribonuclease X -
JLZ95_RS10090 2096648..2097304 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
JLZ95_RS10095 2097406..2097636 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JLZ95_RS10100 2097775..2098149 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JLZ95_RS10105 2098153..2099025 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
JLZ95_RS10110 2099038..2099379 + 342 WP_000976472.1 YebY family protein -
- 2099407..2099678 - 272 - - Antitoxin
- 2099537..2099640 + 104 - - Toxin
JLZ95_RS10115 2099775..2100431 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
JLZ95_RS10120 2100432..2100623 - 192 WP_001338167.1 YebW family protein -
JLZ95_RS10125 2100728..2100964 - 237 WP_001338166.1 DUF1480 family protein -
JLZ95_RS10130 2101082..2102521 - 1440 WP_001397399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T290127 NZ_LR883012:2099537-2099640 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT290127 NZ_LR883012:c2099678-2099407 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References