Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2071176..2071447 Replicon chromosome
Accession NZ_LR883006
Organism Escherichia coli isolate L5_E1779_ETEC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2071306..2071409 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2071176..2071447 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JL014_RS10050 2067731..2068393 - 663 WP_000944256.1 exodeoxyribonuclease X -
JL014_RS10055 2068417..2069073 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
JL014_RS10060 2069175..2069405 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JL014_RS10065 2069544..2069918 + 375 WP_000204699.1 CopC domain-containing protein YobA -
JL014_RS10070 2069922..2070794 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
JL014_RS10075 2070807..2071148 + 342 WP_000976472.1 YebY family protein -
- 2071176..2071447 - 272 - - Antitoxin
- 2071306..2071409 + 104 - - Toxin
JL014_RS10080 2071544..2072200 + 657 WP_000812735.1 protein-serine/threonine phosphatase -
JL014_RS10085 2072201..2072392 - 192 WP_001296140.1 YebW family protein -
JL014_RS10090 2072497..2072733 - 237 WP_001295499.1 DUF1480 family protein -
JL014_RS10095 2072851..2074290 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T290100 NZ_LR883006:2071306-2071409 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT290100 NZ_LR883006:c2071447-2071176 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References