Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2064063..2064334 Replicon chromosome
Accession NZ_LR882990
Organism Escherichia coli isolate L7_E1373_ETEC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2064193..2064296 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2064063..2064334 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLZ97_RS09730 2060618..2061280 - 663 WP_000944256.1 exodeoxyribonuclease X -
JLZ97_RS09735 2061304..2061960 - 657 WP_001718413.1 carbon-nitrogen hydrolase family protein -
JLZ97_RS09740 2062062..2062292 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JLZ97_RS09745 2062431..2062805 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JLZ97_RS09750 2062809..2063681 + 873 WP_001718412.1 copper homeostasis membrane protein CopD -
JLZ97_RS09755 2063694..2064035 + 342 WP_000976472.1 YebY family protein -
- 2064063..2064334 - 272 - - Antitoxin
- 2064193..2064296 + 104 - - Toxin
JLZ97_RS09760 2064431..2065087 + 657 WP_001718411.1 protein-serine/threonine phosphatase -
JLZ97_RS09765 2065088..2065279 - 192 WP_001313035.1 YebW family protein -
JLZ97_RS09770 2065384..2065620 - 237 WP_001295499.1 DUF1480 family protein -
JLZ97_RS09775 2065738..2067177 - 1440 WP_001718410.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T290049 NZ_LR882990:2064193-2064296 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT290049 NZ_LR882990:c2064334-2064063 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References